This volume reprints Fantastic Four #184–188, #190–207, and Annuals #12–13 in black and white, which covers the team’s late-1970s run. The story opens with the FF fighting the Brute and facing Salem’s Seven to protect young Franklin. When the Molecule Man takes over Mr. Fantastic’s body, the team breaks up. The members go their separate ways and each runs into old enemies like Diablo, the Impossible Man, and Namor. They come back together when Dr. Doom returns, and the volume closes with Quasimodo, the Inhumans, the Mole Man, and the Sandman. Issue #189 is left out because it was a reprint issue.