Shiseido's first skincare innovation, Eudermine Activating Essence infuses skin with two types of Hyaluronic Acid for 24 hours of deep hydration, while targeting dark spots with Vitamin C. In just 4 weeks, pores, blemishes, and dullness become less visible.*

Created in 1897 and rooted in Japanese Beauty rituals, Eudermine was a favorite of geishas who used it to protect skin under heavy makeup. With a double dose of Hyaluronic Acid, this ultra-hydrating formula drenches skin in moisture, while Vitamin C brightens and evens complexion. The lightweight texture revitalizes, nourishes, and softens skin—an essential step in any Japanese Beauty skincare routine.

145ml
refill 145ml
Made in Japan