Type: Slow-acting symptomatic treatment for osteoarthritis (SYSADOA)

Active Ingredients:

300 mg of unsaponifiable extracts

100 mg from avocado oil

200 mg from soybean oil

Form: Softgel capsules

Indications

Used for the symptomatic, long-term management of osteoarthritis, especially of the hip and knee

May also be used as adjunctive treatment in managing periodontal (gum) diseases

Benefits & Mechanism of Action

Cartilage Support: Promotes the synthesis of collagen and proteoglycans to help restore cartilage

Anti-inflammatory Action: Reduces the production of inflammatory mediators (e.g., prostaglandins)

Dual Action: Slows cartilage degradation and supports its repair

Pain Relief & Mobility: Improves joint function and can reduce the need for pain medications such as NSAIDs

Dosage & Administration

Recommended Dose: One capsule per day, taken with a meal and water

Onset of Action: Effects may appear after several weeks of continuous use

Minimum Duration: Recommended to be taken for at least 3 months for optimal results

Extended Use: Can be used for 6 months or more if well tolerated and beneficial

Safety & Precautions

Contraindications: Do not use if allergic to avocado, soy, or any other ingredients in the formulation

Side Effects (rare):

Mild gastrointestinal discomfort (nausea, stomach upset)

Soft stool or diarrhea

Rarely: regurgitation with an oily taste or liver-related effects

Drug Interactions: No significant interactions reported; generally well tolerated with other medications

Pregnancy & Breastfeeding: Use not recommended due to insufficient safety data

Usage Tips

Take consistently at the same time each day with food

Evaluate effectiveness after 2–3 months of use

If no improvement occurs after 3 months, consult a healthcare professional

May allow reduction in NSAID use over time