Duane Charles Josephson (June 3, 1942 – January 30, 1997) was an American professional baseball player, a catcher who played for the Chicago White Sox (1965–69) and Boston Red Sox (1971–72) of Major League Baseball.

Josephson batted and threw right-handed. He was born in New Hampton, Iowa, where he attended New Hampton High School. In an eight-season career, Josephson posted a .258 batting average with 23 home runs and 164 RBI in 470 games played.

Forced to retire from baseball at the age of 30 due to pericarditis, Josephson died in New Hampton, Iowa, at the age of 54