Doctor's Best - Double Strength, SAM-e 400mg x 60 Coated Tablets Description Enhance mood and promote cognitive health Healthy metabolism of the major brain transmitters Promote joint comfort and mobility Supports liver health and detoxification Gluten-Free / Soy-Free / Non-GMO Why do I need SAM-e? SAM-e is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAM-e is also required for the biosynthesis of critical neurotransmitters and hormones. SAM-e is a biological compound found in every living cell of the human body, vital to their function, stability and activity and involved in more than one hundred biochemical reactions and specific processes. SAM-e helps promote healthy mood. So if your body is not producing enough SAM-e, you might feel blue or have trouble sleeping. Supplementing with Doctor’s Best SAM-e can help and improve your quality of life.   Suggested Use Adults - Take one (1) tablet daily between meals, or as directed by a health care professional. Do not chew or crush tablet. Nutritional Information Serving Size: 1 Tablet Amount Per Serving % DV SAM-e (S-Adenosyl Methionine disulfate p-toluensulfonate) *400 mg *Percent Daily Values not established Other Ingredients Microcrystalline cellulose, stearic acid, calcium chloride anhydrous, magnesium silicate, magnesium stearate, magnesium hydroxide, flake shellac dewaxed, glycerol, silica, arginine base, sodium alginate, calcium oxide.