English name BAM15

English alias N5,N6-Bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

CAS No. 210302-17-3

molecular formula C₁₆H₁₀F₂N₆O

molecular weight 340.29

appearance

White to off-white powder

• Product Introduction

BAM15 is a novel mitochondrial proton carrier uncoupling agent that significantly increases energy consumption and promotes fat oxidation by disrupting the proton gradient within the mitochondrial inner membrane, without affecting muscle or appetite. Preclinical studies have shown that it can reduce liver lipid accumulation. Oral bioavailability reaches 67%, with better safety than traditional uncoupling agents and no risk of high fever or cytotoxicity.

• Characteristics

1. (1) High purity: BAM15 can obtain high-purity products through refined production processes. High purity means better bioavailability.
2. (2) Efficient decoupling system: As a mitochondrial proton carrier, it disrupts the proton gradient in the inner membrane of mitochondria, promoting the conversion of nutrient oxidation capacity into thermal energy instead of ATP, significantly increasing energy consumption.
3. (3) Metabolic improvement: In animal experiments, oral bioavailability reached 67%, without reducing muscle mass, affecting appetite or body temperature.
4. (4) Low toxicity advantage: Compared to traditional uncoupling agents, there is no risk of high fever or cytotoxicity, and safety is maintained at high doses of 50 μ M without organ damage or neurological side effects.