Waters Acquity UPLC CSH C18 Column, 1.7µm, 2.1 x 50 mm, 186005300 - Used, From Major US Pharmaceutical Company

Enhance your laboratory’s chromatographic performance with this used Waters Acquity UPLC CSH C18 Column (Part Number: 186005300), sourced from the excess inventory of a major US pharmaceutical company. This high-quality column is designed for ultra-performance liquid chromatography (UPLC) and offers exceptional selectivity and efficiency for a wide range of analytical applications. Ideal for researchers and scientists in pharmaceutical, biotechnology, environmental, and food safety industries, this column is in excellent condition and ready to deliver reliable, reproducible results.

Product Description

The Waters Acquity UPLC CSH C18 Column leverages Charged Surface Hybrid (CSH) technology to provide alternate selectivity compared to other reversed-phase UPLC columns. With a 1.7 µm particle size and dimensions of 2.1 mm x 50 mm, this column ensures high-resolution separations, sharp peak shapes, and improved loading capacity, particularly for basic compounds. Its low column bleed and rapid mobile-phase re-equilibration make it an excellent choice for liquid chromatography (LC) and liquid chromatography-mass spectrometry (LC-MS) applications. The column’s robust design and wide pH range make it versatile for analyzing small molecules, peptides, and other biomolecules, ensuring consistent performance even in challenging conditions.

Technical Specifications

• Chemistry: C18
• Separation Mode: Reversed Phase
• Particle Substrate: Hybrid (Charged Surface Hybrid, CSH)
• Particle Size: 1.7 µm
• Pore Size: 130 Å
• Surface Area: 185 m²/g
• Carbon Load: 15%
• pH Range: 1 to 11
• Maximum Pressure: 18,000 psi (1240 Bar)
• Endcapped: Yes
• Silanol Activity: Low
• Particle Shape: Spherical
• Inner Diameter: 2.1 mm
• Length: 50 mm
• Endfitting Type: Parker-style
• USP Classification: L1
• Temperature Range: Up to 80°C (45°C recommended at higher pH for extended column life)
• Applications: Suitable for small molecules, peptides, and biomolecules in pharmaceutical, environmental, and food safety analysis
• Condition: Used, sourced from excess inventory of a major US pharmaceutical company

Key Features

• Charged Surface Hybrid (CSH) Technology: Provides enhanced selectivity and excellent peak shape, especially for basic compounds in low ionic strength mobile phases, without relying on strong ion-pairing agents like TFA.
• High Efficiency: The 1.7 µm particle size ensures superior resolution and fast analysis times, ideal for high-throughput UPLC workflows.
• Wide pH Compatibility: Operates effectively across a pH range of 1 to 11, offering flexibility for method development.
• Low Column Bleed: Optimized for high-sensitivity MS applications, delivering high signal-to-noise ratios.
• Scalability: Seamlessly transferable between UPLC and analytical/preparative HPLC separations, enhancing method development versatility.

Compatible HPLC Systems

The Waters Acquity UPLC CSH C18 Column is designed for use with Ultra-High Performance Liquid Chromatography (UHPLC) and UPLC systems, including:

• Waters Acquity UPLC Systems (e.g., Acquity UPLC H-Class, I-Class, and Classic)
• Other UHPLC systems capable of handling pressures up to 18,000 psi (1240 Bar) and compatible with Parker-style endfittings
• Scalable to HPLC systems for method transfer, such as Waters Alliance HPLC Systems, with appropriate system configurations

Why Buy This Column?

Sourced from a major US pharmaceutical company’s excess inventory, this used Waters Acquity UPLC CSH C18 Column offers exceptional value without compromising performance. Its robust design, high efficiency, and compatibility with a broad range of analytes make it a must-have for laboratories seeking reliable and reproducible chromatographic results. Whether you’re performing routine analyses or developing new methods, this column delivers the precision and versatility needed to excel in demanding applications.

Don’t miss this opportunity to acquire a high-performance Waters Acquity UPLC CSH C18 Column at a fraction of the cost of a new unit.