O’Keeffe’s Working Hands Night Treatment hand lotion for dry hands is a calming yet intense, restorative hand cream that is designed to instantly relieve extremely chapped, dry hands while you sleep. O'Keeffe's Working Hands Night Treatment contains natural grapefruit and lavender oil while being hypoallergenic. Made with deep conditioning oils. This formula won't leave a greasy feel on your hands after you use it. O'Keeffe's Night treatment locks in moisture and works while you sleep. See visible results to your hands in at as little as one night.