On May 2, 1988, USAir (later renamed USAirways and then absorbed by American Airlines) inaugurated service to Las Vegas from Indianapolis and Pittsburgh. The airline requested and received philatelic recognition for the flights and official cachets were provided at all

McDonnell Douglas MD-80 equipment was used on the inaugural flights.

This cover was carried on the inaugural USAir flight from Indianapolis, Indiana to Las Vegas, Nevada (where it was backstamped) and is listed in The American Air Mail Catalogue as AL-D105W.

On February 14, 2013, US Airways Group and AMR Corporation announced that the two companies would merge to form the largest airline in the world. The combined airline carries the American Airlines name.