Cadillac Motor Car Division, or simply Cadillac, is a division of the American automobile manufacturer (GM) that designs and builds luxury vehicles. Its major markets are the United States, Canada and China. Cadillac models are distributed in 34 additional markets worldwide. Historically, Cadillac automobiles General Motorswere at the top of the luxury field within the United States, but have been outsold by European luxury brands including BMW and Mercedes since the 2000s. In 2019, Cadillac sold 390,458 vehicles worldwide, a record for the brand.

Cadillac is among the first automotive brands in the world, fourth in the United States only to Autocar Company (1897) and fellow GM marques Oldsmobile (1897) and Buick (1899). It was named after Antoine de la Mothe Cadillac (1658–1730), who founded Detroit, Michigan. The Cadillac crest is based on his coat of arms.

By the time General Motors purchased the company in 1909, Cadillac had already established itself as one of America's premier luxury car makers. The complete interchangeability of its precision parts had allowed it to lay the foundation for the modern mass production of automobiles. It was at the forefront of technological advances, introducing full electrical systems, the clashless manual transmission and the steel roof. The brand developed three engines, with its V8 setting the standard for the American automotive industry.

Cadillac had the first U.S. car to win the Royal Automobile Club of the United Kingdom's Dewar Trophy by successfully demonstrating the interchangeability of its component parts during a reliability test in 1908; this spawned the firm's slogan "Standard of the World". It won the trophy again in 1912 for incorporating electric starting and lighting in a production automobile.

Cadillac was formed from the remnants of the Henry Ford Company. After a dispute between Henry Ford and his investors, Ford left the company along with several of his key partners in March 1902. Ford's financial backers William Murphy and Lemuel Bowen called in engineer Henry M. Leland of Leland & Faulconer Manufacturing Company to appraise the plant and equipment in preparation for liquidating the company's assets. Instead, Leland persuaded the pair to continue manufacturing automobiles using Leland's proven single-cylinder engine. A new company called the Cadillac Automobile Company was established on August 22, 1902, converting the Henry Ford Company factory at Cass Street and Amsterdam Avenue. It was named after French explorer Antoine Laumet de La Mothe, sieur de Cadillac, who had founded Detroit in 1701.

Cadillac's first automobiles, the Runabout and Tonneau, were completed in October 1902. They were two-seat horseless carriages powered by a 10 hp (7 kW) single-cylinder engine. They were practically identical to the 1903 Ford Model A. Many sources say the first car rolled out of the factory on October 17; in the book Henry Leland—Master of Precision, the date is October 20; another reliable source shows car number three to have been built on October 16. Cadillac displayed the new vehicles at the New York Auto Show in January 1903, where the vehicles impressed the crowds enough to gather over 2,000 firm orders. Cadillac's biggest selling point was precision manufacturing, and therefore, reliability; a Cadillac was simply a better-made vehicle than its competitors.