Brand new in the box, in original sealed and unused packaging. Expiration date: 11/2025
Item No.:  3M21446807E--SW Costs $5,750 through Sartorius. Get your steep discount here!

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Here are the specifications of this product per the Sartorius website:

Sartocon Hydrosart® cassettes are characterized by ultra-low protein adsorption, easy cleaning, higher yields, and long product life. Even with repeated use, the Hydrosart® ultrafiltration membrane maintains its performance without fouling or loss of retention.

Sartocon® cassettes are self-sealing, feature low extractables, and have enlarged feed and retentate ports to lower system pressure drops. They are ideally combined with Sartorius Sartocon holders and systems.

Applications

Typical 100 kDa TFF applications include ultrafiltration and diafiltration of:

• Non-enveloped viruses such as AAV and LV
• Virus-like particles
• pDNA and mRNA
• Blood and plasma
• Protein solutions
• Polysaccharide solutions
• Large mAb constructs
• Removal of contaminants

Hydrosart® Membrane
The Hydrosart® high-performance membrane is a stabilized cellulose-based membrane optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, extremely hydrophilic, non-protein binding, and virtually non-fouling. Membrane depyrogenation can be accomplished using NaOH, even at elevated temperatures. These features make Hydrosart® an ideal membrane for biological applications.

Flow Channel Geometry
The Sartocon® family is available in two flow channel geometry versions. E-Screen filters are predominantly used for protein concentrations above 20% and viscosity conditions greater than 3 cP. ECO-Screen devices, mainly used for water-based protein solutions below 20% protein concentration and viscosities lower than 3 cP, allow for economical, optimized filtration runs.

Available Sizes and Cut-Offs
Sartorius Sartocon® and Sartocube® TFF cassettes are available for pilot- and production-scale applications, as well as in Sartocon® Slice and Sartocon® Slice 200 formats for reduced volume handling.

Cut-Offs:

• E-Screen: 2 | 5 | 10 | 30 | 100 | 300 kDa
• ECO-Screen: 10 | 30 | 100 | 300 kDa

Regulatory Compliance
All product contact materials have passed the current USP Biological Test and Cytotoxicity Test. All materials are BSE- and TSE-free. The filtrate meets or exceeds the currently valid USP and EP standards for sterile Water for Injection with respect to extractable substances, oxidizable substances, and bacterial endotoxins.

Brand: Sartocon®Type: 0.7 m² | ECO Screen
Pack Size: 1
Filter Class: Ultrafilter
Filter Format: Cassettes
Filter Configuration: Sartocon® ECO

Applications

• Industry: Pharma / Biotech

General Specifications

• Cassette Format: Sartocon Cassettes
• Filtration Area: 0.7 m²
• Flow Channel Geometry: Protein concentration <20% or viscosity max. 3 cP

Materials of Construction

• Membrane Material: Hydrosart®
• Integral Frame: Polypropylene (PP)
• Spacer: Polypropylene (PP)
• Sealing Compound: Silicone White (High chemical resistance)

Physicochemical Information

• MWCO: 100 kDa
• Non-Fiber Releasing: Complies with Title 21 of the Code of Federal Regulations (CFR), sections 210.3(b)(6) and 211.72

Operating Conditions

• Maximum Inlet Pressure: 4 bar
• pH Stability: pH 2 – 14

Compliance Information

• Bacterial Endotoxins: < 0.18 EU/mL as determined by the LAL test
• Biological Reactivity: Meets the requirements of the current USP Biological Reactivity Tests <88> for Plastics Class VI (Systemic Injection, Intracutaneous, and Implantation tests)
• Extractables: Total extractables are well below limits established by the current USP under "Sterile Water for Injection"