I am unsure of the use by date as i do not have the box but the cartridges are new and sealed.

The product is a new genuine Canon 245XL 246 black tri-color ink cartridges, sealed in their original packaging. These ink cartridges are compatible with Canon Pixma printers such as iP2820, MG2420, MG2520, and MG2522. The cartridges are manufactured in Japan and comply with the California Prop 65 Warning regarding potential health risks associated with printer ink. With a genuine/original print technology, these cartridges provide high-quality printing results for Canon inkjet printers.