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The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism.  However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited.  This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention.  Support for this position is derived from critical assessment of current cancer theories.  Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.


About the Author:

THOMAS N. SEYFRIED, PhD, has taught and conducted research in the fields of neurogenetics, neurochemistry, and cancer for more than twenty-five years at Yale University and Boston College.


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Cancer as a Metabolic Disease: On the Origin, Management, and Prevention by Thomas N. Seyfried, PhD (Hardcover, English, 2012) presents the metabolic theory of cancer, expanding Otto Warburg's energy metabolism hypothesis to address cancer origins, management, and prevention. This textbook includes brain cancer case studies as proof of principle and discusses similarities to breast and colon cancers due to shared cellular mutations, relevant to biochemistry and preventive medicine readers.