The sand painting in the image is a Navajo (Diné) piece created by an artist named C Tsosie.
The artwork depicts traditional figures, which in ceremonial contexts are referred to as Yei beings or Holy People.
Navajo sand paintings are traditionally an ephemeral part of sacred healing ceremonies, created by medicine men (hatałii) using natural pigments and crushed minerals, and destroyed after the ritual is complete.
The framed, permanent sand art pieces like this one are made for commercial sale and decorative purposes, distinct from the ceremonial ones, to share aspects of the culture and provide a livelihood for artists