Up for auction "Nobel Prize in chemistry" Vladimir Prelog Signed 3X5 Card. This item is
certified authentic by Todd Mueller and comes with their Certificate of
Authenticity.
ES-6947:
Vladimir
Prelog ForMemRS[1] (23 July 1906 – 7 January 1998) was a Croatian-Swiss organic chemist who received the 1975 Nobel Prize
in chemistry for his research into the stereochemistry of
organic molecules and reactions. Prelog was born and grew up in Sarajevo. He lived and worked in Prague, Zagreb and Zürich during his lifetime. Prelog was born in
Sarajevo, Condominium
of Bosnia and Herzegovina, at that time within Austria-Hungary, to Croat parents who were working there. His
father, Milan, a native of Zagreb, was a history professor at
a gymnasium in Sarajevo and later at the University of Zagreb. As
an 8-year-old boy, he stood near the place where the assassination of Franz
Ferdinand occurred. Prelog attended elementary school in
Sarajevo, but in 1915, as a child, Prelog moved to Zagreb (then part of the Austro-Hungary) with his parents. In Zagreb he graduated from
elementary school. At first, he attended gymnasium in Zagreb, but soon
afterwards, his father got a job in Osijek, so he continued his education there. He spent two
years in Osijek gymnasium, where he became interested in chemistry under the
influence of his professor Ivan Kuria.In 1922, as a 16-year-old boy, his first
scientific work was published in the German scientific journal Chemiker Zeitung. The article concerned an analytical
instrument used in chemical labs. Prelog completed his high school education in
Zagreb in 1924. Following his father's wishes, he moved to Prague, where he received his diploma in chemical engineering
from the Czech
Technical University in 1928. He received his Sc.D in 1929. His teacher was Emil Votoček, while his assistant and mentor Rudolf Lukeš
introduced him to the world of organic chemistry.
Upon leaving the Czech Technical University, Prelog worked in the plant
laboratory of the private firm of G.J. Dríza in Prague; few academic positions
were available due to the Great Depression. Prelog was in charge of the production of
rare chemicals that were not commercially available at that time. He worked for
Driza from 1929 until 1935. During the time, he got his first doctoral
candidate, a company owner at Driza. He performed research in his spare time,
investigating alkaloids in cacao bark. Prelog wanted to work in an
academic environment, so he accepted the position of lecturer at the University
of Zagreb in 1935. At the Technical Faculty in Zagreb, he lectured on organic
chemistry and chemical engineering. With the help of collaborators and
students, Prelog started researching quinine and its related compounds. He was financially
supported by the pharmaceutical factory "Kaštel",
currently Pliva. He developed a financially successful method of
producing Streptazol, one of the first commercial sulfonamides. In 1941,
while at Zagreb, Prelog developed the first synthesis of adamantane, a hydrocarbon with an unusual structure that was isolated
from Moravian oil fields. In 1941, in the midst of World War II, Prelog was invited to lecture in Germany
by Richard Kuhn. Shortly
afterwards, Lavoslav Ružička, whom
Prelog asked for help, invited Prelog to visit him on his way to Germany. He
and his wife used those invitations to escape to Zürich in Switzerland. With Ružička's help, he gained
support from CIBA Ltd. and started to work in the
Organic Chemistry Laboratory in the Swiss Federal Institute of Technology (ETH,
or Eidgenössische Technische Hochschule). Prelog was able to
separate the chiral enantiomers of Tröger's base in 1944 by chromatography on an optically active substrate. With this chiral resolution, he was able to prove that not only carbon but also nitrogen atoms can be the chiral centre in a molecule,
which had been speculated for several years. His relationship with Ružička
helped him climb up the academic hierarchical ladder. Starting as an assistant,
he became Privat-Dozent, Titularprofessor, associate
professor, and in 1952 full professor. In 1957 he succeeded Ružička as head of
the Laboratory. Since Prelog disliked administrative duties,
he implemented rotating chairmanship in the ETH. Prelog joined the ETH at the right time, since
Ružička's Jewish co-workers left the country and went to the United States, so
Prelog filled the vacuum they left.