The yellow toner is not sealed but unused.
The remaining 3 are completely sealed.

• Product Name: E-Z Ink compatible toner cartridges replacement for HP 202X 202A CF500X CF500A
• Package Contents: 1 x User Guide, 1 x 202X Black, 1 x 202X Cyan, 1 x 202X Magenta, 1 x 202X Yellow (Total 4 Pack)
• Page Yield: Black is 3,200 pages per cartridge and Color is 2,500 Pages per cartridge at 5% coverage
• Compatible Printers: HP LaserJet Pro MFP M280nw, M281dw, M281fdw, M281cdw,Color LaserJet Pro M254dw,M254dn,M254nw,M281fdn Laser Printer