As Mother's Day nears, a group of seemingly-unconnected people in Atlanta come to terms with their relationships with their mothers.
Sandy is a divorced mother of two sons, Mikey and Peter, whose ex-husband, Henry has recently married a younger woman, Tina. Still getting used to this, she meets Bradley, a former Marine, in the supermarket. Bradley's wife Dana, a Marine Lieutenant, died a year previously, leaving him with their two daughters, Vicky and Rachel.
Kristin, adopted from birth, has her own daughter, Katie, and mulls over marrying the father of her child, Zack. She considers her life incomplete and her friend Jesse encourages her to search for her birth mother. Jesse also happens to be Sandy's best friend.
Jesse is married and has a son, Tanner, with Russell, who is Indian. Her sister Gabi is married to her wife Max and has a son, Charlie. When their racist, homophobic parents, Earl and Florence, unexpectedly show up, they have to come to terms with who their daughters are and the partners they have chosen.