This medicine is not suggested to used in some situations, like if you have diseases like T.B. Asthma , Ulcer, Dengue , Malaria, Typhoid, Cancer, Migraine, Depression, Diabetes And any problem of Heart or Kidney , If you have any minor or major operation in last 1year or any major disease which required frequently doctor consultancy, Pregnant or ladies having 1.5-year-old or younger baby are not suggested to use this medicine.