Mireille Mathieu's singing style is characterized by a powerful voice, a wide vocal range, and a unique vocal technique, including a notable use of the uvular trill. Often performing chanson and pop standards, she is known for her soulful, strong delivery and ability to adapt her voice to a variety of genres, leading her to be called "the Sparrow of Avignon" and the successor to Édith Piaf. 

From the beginning, Mireille Mathieu was born to be a singer. As she herself would say, her professional career, which begain on November 21, 1965, has for over 40 years been "a fairy tale come true." Born in Avignon the eldest daughter of Marcelle and Roger Mathieu's 14 children, Mireille gave her first public performance when she was 4 years old at Midnight Mass.

She was quickly hailed as the next Édith Piaf and her 1965 performance run at the Paris Olympia sparked her recording relationship with Barclay Records, where her first album sold over 1 million copies.

In 1997, Mireille was nominated and given the "Chevalier de l'Ordre National du Mérite et des Arts et des Lettres" and decorated with "The Legion of Honor" for her service to the Nation of France." Of her reception by Pope John Paul II, His Holiness has said, "She is the singer of love and peace."