This hardcover volume, edited by Stefan H.E. Kaufmann, Barry T. Rouse, and David L. Sacks, provides a synthetic narrative of the innate and adaptive immune responses to infection. Published by ASM Press in 2011, this 1st edition integrates and updates material from previous foundational texts to cover the dynamic developments in microbiology. It serves as a comprehensive academic resource for students and professionals focusing on immunology and infectious diseases.