Her 2 y carcinoma gástrico: Relación entre la exprexión del Her 2 y las características anatomopatológicas del carcinoma gástrico

Condition: LIKE_NEW
Author: Ever Marino Olivera Fonseca, Yanelys Olivera Fonseca, Carlos A Domínguez Álvarez
Publisher: Editorial Académica Española
ISBN/EAN: 6200359865
Product Type/Binding: Paperback
Publish Year: Januar 2020
Language: Spanish
Size: 1 cm x 15 cm x 22 cm
Weight: 262 g

Description of the product

Se realizó un estudio de observacional, prospectivo y descriptivo en el servicio de anatomía patológica del hospital clínico quirúrgico Hermanos Ameijeiras, donde se identificó la relación entre la expresión del HER2 y las características anatomopatológicas del carcinoma gástrico en las biopsias de los pacientes seleccionados. Fueron incluidos 150 pacientes mayores de 18 años, de ambos sexos, con diagnóstico histológico de carcinoma gástrico o de la unión gastroesofágica. La mediana de edad en la muestra fue de 64 años y predominó el sexo masculino (55.3%) de la raza blanca (60.0%). En cuanto a las características anatomopatológicas predominaron los tumores del cuerpo gástrico(31,3%), tipo difuso(59,3%), pobremente diferenciados(46,7%), ulcerados(92,7%) e infiltrantes (97,7%).La frecuencia de expresión del HER2 fue de un 18% y se encontró asociación positiva entre esta condición y el grado de diferenciación, el subtipo histológico y la no presencia de células en anillo de sello en las biopsias analizadas (p=0.000). No encontramos diferencias entre esta serie y otros estudios reportados en la literatura en cuanto a características demográficas y anatomopatológicas.

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